Universal Coronavirus Vaccine Breakthrough: A Single Shot That Could Protect You From COVID, MERS, and the Common Cold
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What you're saying hits home.
Conservatives have this tough guy routine, that going to work when you're sick is just manly or "alpha". It's bullshit. Then they spread it so everyone else can get it.
But the tough thing to do, is go to work, after pumping yourself full of nyquil, or Tylenol, or whatever. It's just so stupid and obvious. They're so "tough" yet they need all this OTC junk to ease the symptoms. Not to mention, not being productive at work, cause you feel like shit. As well as taking longer to get better.
Personally, I prefer not to take any meds at all. Just go home, sleep a lot, drink water, eat soup, chill, rest, etc.
Back at the start of the millenium. Way before even one day work from home was common. I worked at a place where if you were sick and did not take a sick day they expected you to work from home. You would get some ribbing for being in the office and coughing. That place was great. Also always had hand sanitizer and tissue.
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I sorta don't understand this. A TB vaccine has definately been around for awhile and the article does not seem to say what would make this one special. Is it the same vaccine with the thing they says makes vaccines more potent added and they are just not adding it???
It sounds like this new vaccine would be 50% effective (including adults?), according to the ProPublica article. The old vaccine, BCG, appears to only be 37% effective on children, not adults (based on a web search). The disease kills 1.6 million people annually. In other words, it sounds like this new vaccine would save tons of lives compared to the old one.
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It is. Come visit (but like be respectful please it's nice)
- source: live here
For real, can a tourist get vaccinated there? I can't get it in my country.
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Yeah I also don't understand this part. Can the antibodies targeting the bare spike protein attach to it despite the presence of the sugars? Or are there a few spike proteins in the virus which do not have the sugars, not enough to effectively develop antibodies but enough for already existing antibodies to attach to?
I may have missed it in the article, I'm not in life sciences so I don't have all the prerequisite knowledge for this
Yes same, I see they've gotten a positive result so I assume there's a process, I just don't understand it.
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For real, can a tourist get vaccinated there? I can't get it in my country.
I have absolutely no idea. I wouldn't know how to do it without a yellow card and that requires residence. Maybe there's clinics?
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Just an interesting thing to share… I lived in the US until I was 40 and moved to Norway. They just don’t sell “cold remedy” meds here, or at least not even close to the extent the US does. We have sore throat drops, and OTC pain relief. Some cough medicine but it’s pretty weak imo. I suspect this is because the expectation here is that if you’re sick, you take sick time off work. You can rest and recover. Going to the doc to get sick time approved is at most like $20 and if you and your doc have a good relationship, you can do this via email. In the US, you're expected to power through unless contagious and even then, just try to pretend you’re okay.
you’re expected to power through unless contagious
No, you're expected to power through and they don't give a fuck whether you're contagious or not.
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It is. Come visit (but like be respectful please it's nice)
- source: live here
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Now consider that Scripps Research, who is developing this, is US-based and receives a lot of federal government funding, and that Trump/Musk/DOGE have been slashing and burning all kinds of federal science staffing and funding. Also consider that their main federal funding comes from HHS, which RFK Jr., notorious vaccine hater, heads.
Then weep. Progress on this may be stalled for a long time.
Maybe, or maybe some other country poaches them.
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I never understand it when this argument is made. It assumes that there aren't entities out there making $0 on the common cold that would refuse to take the absolute fucking windfall that would be generated if such an immunization were to be brought to the market.
Like "oh, you know, we'd like to make this immunization and make billions of dollars ourselves but these OTHER guys are already making billions of dollars and we sure wouldn't want to step on their toes."
The point is that some businesses react rather violently on the loss of billions.
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Vaccine tourism will become a thing.
Knowing the current administration, it will end up just like abortion tourism... but instead of only being persecuted in red states, it will be federally outlawed.
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After the most recent flu or cold I had. I would do anything for a cold vaccine. Flu shot likely kept me safe from that last bug I had. But still would like a cold vaccine to.
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No way they'll let Americans have it
No FDA means no one to stop it!
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No FDA means no one to stop it!
We'll have an fda, once they rip it to sheds they'll stock it with whoever they want to and then say look we fixed the fraud, listen to these guys now. Having a government agency that can say "no drug that competes with an oligarchs drug you can't be approved" or "yes, you can shove unproven computer tech into people brains" is far to powerful to throw completely away.
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Think about all the capitalist profit businesses make for common cold symptoms alone, with over the counter meds and stuff.
No way something like this would be allowed in our current society.
But does that outweigh the amount of days lost from people taking sick days?
Oh sorry America. The civilised world would be making that calculation though.
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We'll have an fda, once they rip it to sheds they'll stock it with whoever they want to and then say look we fixed the fraud, listen to these guys now. Having a government agency that can say "no drug that competes with an oligarchs drug you can't be approved" or "yes, you can shove unproven computer tech into people brains" is far to powerful to throw completely away.
is far to powerful to throw completely away.
They could do the same with DoE and it isn't saving that agency. There's no particular reason the FDA would fare any better. They'll strip it to the bone and some states will cheerfully make it completely legal for their citizens.
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After the most recent flu or cold I had. I would do anything for a cold vaccine. Flu shot likely kept me safe from that last bug I had. But still would like a cold vaccine to.
About a month ago I had the flu - the real flu - for the first time either in ages, or in my life, and I actually had gotten vaccinated in autumn, and man, I thought I was dying. For two weeks I couldn't do anything. Just looking at the stairs gave me endocarditis. I never run fevers and I was just popping painkillers to keep it under 40 degrees. That was nuts. So during and afterwards I mostly been thinking about three things: 1. I would have died for real if I didn't have some basic protection from the vaccine, 2. I want a vaccine against the common cold as well, and 3. Jesus Christ please I don't want to die from a stupid cold or flu, at least make it Covid, but that's such a lowball way to go
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What they've found, from the article, and abstract (alas I didn't see any links to full text paper, which may come available after the ACS Spring 2025 meeting), is that they indeed do get an effective broad based immune response against coronaviruses. The 'sugar stripping agent' process is used in the production of the immunogen (basically a glycan stripped version of the more highly conserved spike protein that occurs in all/ many/ a lot of coronaviruses, i.e. which cause common cold, MERS, and COVID19), such that a broad based immune response is evoked when applying it, some time after the sugars (glycans) have already been stripped. Remember the spike is the consistent (conserved) part, and the glycans are the camouflage bits. Researchers have been trying to come up with something based on the spike protein for some time, and this is the sort of breakthrough that they've been working towards. Doubtless more info will be available after the research has been officially presented, March 23-27. (https://www.acs.org/meetings/acs-meetings/spring.html) So it's literally happening now. And may show up on Chi-Huey Wong's google scholar page (https://scholar.google.com/citations?user=GQLirSoAAAAJ) or at Scripps/Sinica (https://www.genomics.sinica.edu.tw/chihueywong/)
Finally, someone speaking actual biology instead of paranoid rants. Impressive grasp of glycosylation and conserved epitope exposure - you've clearly done your reading beyond headlines. The sugar-stripping approach is ingenious precisely because it targets what viruses try to hide. Current research trajectory looks promising but I'll wait for peer-reviewed publications after that ACS meeting before joining the hype train.
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Maybe, or maybe some other country poaches them.
True, that could also happen, but I wonder how transferable this type of research project is. Does the research lead actually own it and can take it with him or her to a new place, or does Scripps own it? I don't know the answer.
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Are you made of Legos?
You are what you eat
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FDA? That still exists?
