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  3. Who tried a generic extended-release methylphenidate instead of their usual?

Who tried a generic extended-release methylphenidate instead of their usual?

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  • A This user is from outside of this forum
    A This user is from outside of this forum
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    wrote last edited by
    #1

    My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

    Can it really be so much different? Both claim to have a 50 % instant-release part.

    Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

    K spankmonkey@lemmy.worldS S C S 5 Replies Last reply
    2
    • A [email protected]

      My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

      Can it really be so much different? Both claim to have a 50 % instant-release part.

      Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

      K This user is from outside of this forum
      K This user is from outside of this forum
      [email protected]
      wrote last edited by
      #2

      Generic extended release methylphenidate was what my primary care doc first tried me on. I noticed it a little and thought ok, it's still really hard to function. What do people mean that getting on medication was a game changer for them?

      After about a year of this, trudging through my day still, I got in to see a psych about a month ago who switched me to Vyvanse, and holy cow. I'm functioning again! Wtf?!

      I will say that my sleep has suffered some, but that's a little bit on me for not taking my meds early enough in the day.

      spankmonkey@lemmy.worldS R 2 Replies Last reply
      1
      • A [email protected]

        My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

        Can it really be so much different? Both claim to have a 50 % instant-release part.

        Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

        spankmonkey@lemmy.worldS This user is from outside of this forum
        spankmonkey@lemmy.worldS This user is from outside of this forum
        [email protected]
        wrote last edited by
        #3

        I am on the extended release (ER) for methylphenidate on a high dose for like 20 years and for me it lets me focus while it is working.

        Sustained release (SR) does not work nearly as well for me. Standard release wears off way too fast.

        People have very different rates of success or side effects so yes, it really could be that different! It sounds like this isn't the right one for your kiddo.

        1 Reply Last reply
        2
        • K [email protected]

          Generic extended release methylphenidate was what my primary care doc first tried me on. I noticed it a little and thought ok, it's still really hard to function. What do people mean that getting on medication was a game changer for them?

          After about a year of this, trudging through my day still, I got in to see a psych about a month ago who switched me to Vyvanse, and holy cow. I'm functioning again! Wtf?!

          I will say that my sleep has suffered some, but that's a little bit on me for not taking my meds early enough in the day.

          spankmonkey@lemmy.worldS This user is from outside of this forum
          spankmonkey@lemmy.worldS This user is from outside of this forum
          [email protected]
          wrote last edited by [email protected]
          #4

          It is funny because Vyvanse gave me weird side effects without any benefit (too long ago to remember) while the ER methylphenidate had a progressively more effective benefit with zero side effects for me as the dosage went up to the one I settled on. Been taking it for years and have to justify to insurance once a year that no, I don't want to try the ones that didn't work just let me stay on this.

          Glad to hear you found one that works for you!

          1 Reply Last reply
          2
          • A [email protected]

            My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

            Can it really be so much different? Both claim to have a 50 % instant-release part.

            Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

            S This user is from outside of this forum
            S This user is from outside of this forum
            [email protected]
            wrote last edited by
            #5

            Looks like the post is referring to a Medikinet product that could also be described as delayed release or modified release, instead of the word which was censored in the post. In case anyone else was confused like me.

            1 Reply Last reply
            1
            • K [email protected]

              Generic extended release methylphenidate was what my primary care doc first tried me on. I noticed it a little and thought ok, it's still really hard to function. What do people mean that getting on medication was a game changer for them?

              After about a year of this, trudging through my day still, I got in to see a psych about a month ago who switched me to Vyvanse, and holy cow. I'm functioning again! Wtf?!

              I will say that my sleep has suffered some, but that's a little bit on me for not taking my meds early enough in the day.

              R This user is from outside of this forum
              R This user is from outside of this forum
              [email protected]
              wrote last edited by
              #6

              You can try something like 1mg extended release melatonin for sleep

              1 Reply Last reply
              2
              • A [email protected]

                My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

                Can it really be so much different? Both claim to have a 50 % instant-release part.

                Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

                C This user is from outside of this forum
                C This user is from outside of this forum
                [email protected]
                wrote last edited by
                #7

                My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

                Unrelated to your question, but please, I need to know what word dot ml decided to filter out lol

                therapygary@lemmy.blahaj.zoneT otter@lemmy.dbzer0.comO 2 Replies Last reply
                1
                • C [email protected]

                  My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

                  Unrelated to your question, but please, I need to know what word dot ml decided to filter out lol

                  therapygary@lemmy.blahaj.zoneT This user is from outside of this forum
                  therapygary@lemmy.blahaj.zoneT This user is from outside of this forum
                  [email protected]
                  wrote last edited by [email protected]
                  #8

                  The "r word" (retard) as in slow release

                  C 1 Reply Last reply
                  2
                  • therapygary@lemmy.blahaj.zoneT [email protected]

                    The "r word" (retard) as in slow release

                    C This user is from outside of this forum
                    C This user is from outside of this forum
                    [email protected]
                    wrote last edited by [email protected]
                    #9

                    Of course

                    Edit: they'll filter it even if you're french

                    1 Reply Last reply
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                    • A [email protected]

                      My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

                      Can it really be so much different? Both claim to have a 50 % instant-release part.

                      Medikinet removed has a similar curve as Ritalin LA with a stronger peak between hour 3 and 6. The Zentiva isn't even documented that well. German article with interesting comparison graphs: https://www.ppt-online.de/heftarchiv/2022/04/individuelle-adhs-therapie-mit-methylphenidat-*removed*praeparaten.html

                      S This user is from outside of this forum
                      S This user is from outside of this forum
                      [email protected]
                      wrote last edited by
                      #10

                      Adult on time release generic methylphenidate here. I notice it usually starts working about 45 minutes after ingestion. Instant release only really means as soon as it begins to be digested and everybody's body is different.

                      Also remember, don't mix it with caffeine or the effects will be greatly reduced.

                      1 Reply Last reply
                      1
                      • C [email protected]

                        My child had to switch from Medikinet removed to the Zentiva version. Teachers said the generic is hardly working at all.

                        Unrelated to your question, but please, I need to know what word dot ml decided to filter out lol

                        otter@lemmy.dbzer0.comO This user is from outside of this forum
                        otter@lemmy.dbzer0.comO This user is from outside of this forum
                        [email protected]
                        wrote last edited by
                        #11

                        Same. "XR"?

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