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  3. Does a small amount of alcohol-drink help another polar substance taken sublingually help permeate more/good

Does a small amount of alcohol-drink help another polar substance taken sublingually help permeate more/good

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    wrote on last edited by [email protected]
    #1
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      wrote on last edited by
      #2

      Do the buccals absorb better if theyre dry or submerged in the liquid?

      tidbit@mander.xyzT 1 Reply Last reply
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        Do the buccals absorb better if theyre dry or submerged in the liquid?

        tidbit@mander.xyzT This user is from outside of this forum
        tidbit@mander.xyzT This user is from outside of this forum
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        wrote on last edited by [email protected]
        #3

        As someone who loves OChem and Molecular/Cellular Bio, this is right up my alley! But without knowing the specific substance being taken along with the alcohol, this can only be discussed in general terms. Alcohol, particularly ethanol, is known to have unique properties that can influence the permeability of biological membranes. When a polar substance is combined with a small amount of alcohol, it tends to enhance the solubility of that substance, potentially facilitating its absorption. Ethanol can also disrupt the lipid bilayer of cell membranes, which may allow for better penetration of polar molecules. Additionally, the absorption is typically better when these substances are submerged in a liquid rather than being dry, as hydration and solubility play crucial roles in sublingual absorption. Yet, it's important to approach this with cautiously considering the potential impact of alcohol on the mucous membranes and overall health, especially over time.

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        • tidbit@mander.xyzT [email protected]

          As someone who loves OChem and Molecular/Cellular Bio, this is right up my alley! But without knowing the specific substance being taken along with the alcohol, this can only be discussed in general terms. Alcohol, particularly ethanol, is known to have unique properties that can influence the permeability of biological membranes. When a polar substance is combined with a small amount of alcohol, it tends to enhance the solubility of that substance, potentially facilitating its absorption. Ethanol can also disrupt the lipid bilayer of cell membranes, which may allow for better penetration of polar molecules. Additionally, the absorption is typically better when these substances are submerged in a liquid rather than being dry, as hydration and solubility play crucial roles in sublingual absorption. Yet, it's important to approach this with cautiously considering the potential impact of alcohol on the mucous membranes and overall health, especially over time.

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          wrote on last edited by
          #4

          Do wine and like zopiclobe

          L fullsquare@awful.systemsF thetimeknife@lemmy.worldT 3 Replies Last reply
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            Do wine and like zopiclobe

            L This user is from outside of this forum
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            wrote on last edited by [email protected]
            #5

            Careful with that one buster, benzos and booze are a fast track to a forever snooze.

            Edit: ok my bad, zopiclone is a nonbenzo after I double checked but don't mess too hard with GABA receptor stuff, those cheeky cunts have a way of messing back with ye.

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              Do wine and like zopiclobe

              fullsquare@awful.systemsF This user is from outside of this forum
              fullsquare@awful.systemsF This user is from outside of this forum
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              wrote on last edited by
              #6

              you shouldn't mix alcohol and zopiclone mate you're gonna die from this

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                Do wine and like zopiclobe

                thetimeknife@lemmy.worldT This user is from outside of this forum
                thetimeknife@lemmy.worldT This user is from outside of this forum
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                wrote on last edited by [email protected]
                #7

                Do not mix those drugs. They have a high risk of stopping your ability to breathe. Alcohol does not mix with drugs that act on GABA.

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