Universal Coronavirus Vaccine Breakthrough: A Single Shot That Could Protect You From COVID, MERS, and the Common Cold
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Doesn't chickenpox turn into shingles by infecting the nervous system?
Could long covid be related to that?
The virus that causes chicken pox, lies dormant in your nervous system, where your immune system can’t get it, for decades. Then much later in life the virus can reactivate, infect along those nerves, causing shingles.
This is the important part of the chicken pox vaccination the we don’t talk about nearly enough.
- If you get chicken pox, you’ll probably be ok (although not everyone is) and get over it, becoming immune. But the virus will still lurk, opening you to shingles attacks when you’re much older
- if you get the vaccination, you’ll probably not only not get chicken pox, but will also not get shingles
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Drowning is probably the best way to go excluding the obvious opiate overdose forever sleepy time. It's not drawn out like freezing to death.
I don't fancy spending a few minutes trying to breathe water.
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is far to powerful to throw completely away.
They could do the same with DoE and it isn't saving that agency. There's no particular reason the FDA would fare any better. They'll strip it to the bone and some states will cheerfully make it completely legal for their citizens.
We'll see. I feel like there's more value keeping around the institution which says what substances and food you can or cannot sell and who can or cannot sell them than there is in the institution dedicated to making sure everyone has schooling, indoctrination is easier if people are stupid.
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The virus that causes chicken pox, lies dormant in your nervous system, where your immune system can’t get it, for decades. Then much later in life the virus can reactivate, infect along those nerves, causing shingles.
This is the important part of the chicken pox vaccination the we don’t talk about nearly enough.
- If you get chicken pox, you’ll probably be ok (although not everyone is) and get over it, becoming immune. But the virus will still lurk, opening you to shingles attacks when you’re much older
- if you get the vaccination, you’ll probably not only not get chicken pox, but will also not get shingles
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I wonder how this could help those with long COVID.
Many long COVID infections are causing/caused significant damage to organs (https://pmc.ncbi.nlm.nih.gov/articles/PMC11834749/). A vaccination isn't going to reverse organ damage.
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Yeah I also don't understand this part. Can the antibodies targeting the bare spike protein attach to it despite the presence of the sugars? Or are there a few spike proteins in the virus which do not have the sugars, not enough to effectively develop antibodies but enough for already existing antibodies to attach to?
I may have missed it in the article, I'm not in life sciences so I don't have all the prerequisite knowledge for this
from what ive gathered from the abstract,t he glycosolation prevents a more robust immune response, less antibody titers, when they removed it they noticed the immune system recognizes the spike proteins more easily so a stronger immune response and more antibody produced, and a longer titre of antibodies.
first when they removed the "glycans" it revealed more of the protein of the virus, so the immune system recognizes different parts or more of it, so stronger and longer last immune response. the conserved parts is the parts of the proteins that dont mutate much so its easier to become immune to it, the sugars originally hid that part.
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Finally, someone speaking actual biology instead of paranoid rants. Impressive grasp of glycosylation and conserved epitope exposure - you've clearly done your reading beyond headlines. The sugar-stripping approach is ingenious precisely because it targets what viruses try to hide. Current research trajectory looks promising but I'll wait for peer-reviewed publications after that ACS meeting before joining the hype train.
i was thinking the same about the abstract, the glycans were shielding the conserved parts epitopes that arnt prone to mutations,
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FDA approval in never.
I'm not even bothering with FDA recommendations anymore with Kennedy in charge. I'll be reading the Canada Health and NHS (UK) notices. If it means crossing a national border to get a vaccine, I'm onboard.
there are some international pharm companies that produces vaccines, im sure they wouldnt mind doing it,. glaxo kline smith is one of them, although people have dislike the company for many reasons.
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Theoretically, this could approved in Europe, which is fine for me. But I doubt the pharmaceutical industry will let a working, permanent immunisation against the common cold happen. That would mean billions and trillions of lost business.
its pretty hard to vaccinate against the common cold, since coronavirus only represents like 15ish percent, the majority are all rhinoviruses there arnt any vaccines for those because theres too many strains(like 200+) to deal with, and also its so self-limiting its not worht it to produce anyway, in addition to trying to figure out which virus is causing the cold and which strain. also there a bunch of other viruses that causes colds, like entero,adeno, parainfluenza, RSV,,,etc.
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Meanwhile, in the U.S. I'm sitting here wondering if we'll even have a flu shot available for next winter, let alone a new vaccine that can protect from Covid and the common cold.
they actually did end up having the meeting on the 13th:
will it happen? idk but it's a good sign at least
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I sorta don't understand this. A TB vaccine has definately been around for awhile and the article does not seem to say what would make this one special. Is it the same vaccine with the thing they says makes vaccines more potent added and they are just not adding it???
i think only the USa DOESNT routinely vaccinate it against it, because they havnt found much efficacy, TB endemic areas do vaccinate against it, but it has limited efficacy. on the plus side, it is used with cancer therapy as a indirect effect to stimulate the immune system.
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Just an interesting thing to share… I lived in the US until I was 40 and moved to Norway. They just don’t sell “cold remedy” meds here, or at least not even close to the extent the US does. We have sore throat drops, and OTC pain relief. Some cough medicine but it’s pretty weak imo. I suspect this is because the expectation here is that if you’re sick, you take sick time off work. You can rest and recover. Going to the doc to get sick time approved is at most like $20 and if you and your doc have a good relationship, you can do this via email. In the US, you're expected to power through unless contagious and even then, just try to pretend you’re okay.
dextrotomorphan, is the cough, i find it has little effect on coughs. i believes its the 1st generations(diphenhydramine, doxylamine,bropheneramine,,,etc) anti-histamine that is preventing the smptoms, because also prevents mucus production via anti-cholingernic effects and the cough, besides the fever.
and pehnyleprine has no effect on you what so ever, you need the pseudoephedrine
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The US is following the (modern) russian model.
Outside of war time concerns over draft dodgers (which is not restricted to totalitarian regimes), there are no "extra" restrictions on citizens outside of needing a passport. There ARE restrictions placed on "political opponents" but that can be considered an extension of the "normal" restrictions on people with pending legal issues and so forth and gets into a greater discussion of the role of law in a society.
No. The big restriction is monetary. Which is also how control is maintained and oligarchs are protected.
The US is rapidly speedruning a christofacist oligarchy. But that is still going to be a lot closer to a Russia or a China than a North Korea. The latter is possible and should be feared but would require a massive shift that takes away the "Things are bad for me but they are worse for Them" that conservatives globally depend on.
russia mostly, since alot of red state more or less mirrors russia in some form. and they are the ones that had a hand in gops rise to power, and continuance, and funding right wing groups(white supremecist, alt-right). china has thier own problems, and would rather steal tech instead of developing it themselves.
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Vaccine tourism will become a thing.
medical tourism to places like india, thailand,,,etc for dental and medical treatment.
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Make sure they're also countries that will give vaccines to foreigners. I had a hell of a time getting routine flu shots in Spain, Hungary and Thailand. The systems are often set up with the assumption that you're a citizen or have a national healthcare ID of some sort. Without that, good luck finding a clinic who will give you a shot.
india and thailand caters to medical tourism, i asusme alot will be either going to canada(maybe) or asia.
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After the most recent flu or cold I had. I would do anything for a cold vaccine. Flu shot likely kept me safe from that last bug I had. But still would like a cold vaccine to.
cold might be harder since theres different viral species that causes it, and rhinoviruses alone account for 80-90% have 99 different types. flu is worst thought since its symptoms are more severe, and dangerous to some people.
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I wonder how this could help those with long COVID.
long covid, aka sequelae (medical term) means you had a long last complication that seperate from the virus. the inflammation couldve damaged parts of your body you are chronically suffering from. it might not help, since its not caused by the virus anymore.
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Doesn't chickenpox turn into shingles by infecting the nervous system?
Could long covid be related to that?
different issues. varicella can cause shingles, when it travels to your dorsal root ganglia near your spine or the ganglia in your head,or rarely it can become dormant in your autonomic nervous system.
varicella, a herpes isnt the same thing as coronavirus. long covid is just laymen terms for complications or sequalae. Covid can trigger shingles, because your immune system is fighting the covid virus instead of shingles.
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The virus that causes chicken pox, lies dormant in your nervous system, where your immune system can’t get it, for decades. Then much later in life the virus can reactivate, infect along those nerves, causing shingles.
This is the important part of the chicken pox vaccination the we don’t talk about nearly enough.
- If you get chicken pox, you’ll probably be ok (although not everyone is) and get over it, becoming immune. But the virus will still lurk, opening you to shingles attacks when you’re much older
- if you get the vaccination, you’ll probably not only not get chicken pox, but will also not get shingles
the varicella vaccine prevents severe infections, but its not entirely protective against it, it just makes you asymptomatic, and once you get reinfected it can still become dormant, and get hsingles, just less chances of getting it.
